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PotentantagoNISTofthenoradrenalintransporter(IC50=55nM);alsodisplaysantagonistactivityatthe5-HTanddopaminetransporters(IC50valuesare117nMand910nMrespectively).Orallyactive.Exhibitsantinociceptiveandantiallodynicactivityinrodentmodelsofacute,persistent,andchronicpain.
BicifADInehydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 209.72 |
| Formula | C12H15N.HCl |
| Storage | DesiccateatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 66504-75-4 |
| PubChemID | 47952 |
| InChIKey | OTZOPAFTLUOBOM-UHFFFAOYSA-N |
| Smiles | CC(C=C3)=CC=C3C12CNCC1C2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.97 | 100 | |
| water | 20.97 | 100 |
Thefollowingdataisbasedontheproductmolecularweight209.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.77mL | 23.84mL | 47.68mL |
| 5mM | 0.95mL | 4.77mL | 9.54mL |
| 10mM | 0.48mL | 2.38mL | 4.77mL |
| 50mM | 0.1mL | 0.48mL | 0.95mL |
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