PotentandselectiveRARγreceptoragonist(Kivaluesare150,1500and2750nMforRARγ,RARβandRARαreceptorsrespectively).Activatestranscriptionalactivity(AC50=1.8nM).
M.Wt | 398.49 |
Formula | C27H26O3 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 107430-66-0 |
PubChemID | 24868309 |
InChIKey | YSGDXEKQTNMRQN-UHFFFAOYSA-N |
Smiles | OC(=O)C1=CC=C(C=C1)C1=CC=C2C=C(C(O)=CC2=C1)C12CC3CC(CC(C3)C1)C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 39.84 | 100 |
Thefollowingdataisbasedontheproductmolecularweight398.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.51mL | 12.55mL | 25.09mL |
5mM | 0.5mL | 2.51mL | 5.02mL |
10mM | 0.25mL | 1.25mL | 2.51mL |
50mM | 0.05mL | 0.25mL | 0.5mL |
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