您好,欢迎您进入188进口试剂采购网网站! 服务热线:4000-520-616
蚂蚁淘商城 | 现货促销 | 科研狗 | 生物在线

JPT/RepliTope™ EBV (EBNA3b)/RTEBVEBNA3b/

RepliTope™EBV(EBNA3b)

ProductCode:RT-EBV-EBNA3b

Peptidemicroarraydisplaying234peptidesderivedfromapeptidescan(15merswith11aaoverlap)throughEpstein-Barrnuclearantigen4(EBNA3b)(Swiss-ProtID:Q1HVG4)ofEpstein-Barrvirus(HHV4).
Amount:1peptidemicroarray(eachpeptideisdeposited3xpersubarray,4subarraysperslide)+dummyslideandspacers(neededforincubation)
Purity:Freeoftruncatedsequences
DeliveryFormat:Peptidesimmobilizedontoglassslide(3x1inches;75by25mm)
Application(s):Immunemonitoring,Humoralimmuneresponse,SeroMarkerdiscovery,Antibodyepitopediscovery,Bindingexperiments
Indication(s)/Topic(s):Infection,Cancer,Hodgkinslymphoma,Burkittslymphoma,Nasopharyngealcarcinoma,Dermatomyositis,Systemiclupuserythematosus,Rheumatoidarthritis,Sjgrenssyndrome,Multiplesclerosis
DeliveryTime:10-12days

RepliTope™PeptideMicroarrays
JPTPeptideTechnologiesappliesitsuniquepeptidemicroarrayplatformtogeneratepeptidemicroarraysonglassslidesforbiomarkerdiscovery,immunomonitoringanddetectionandvalidationofproteininteractions.Peptidesareimmobilizedonglassslidesviaaflexiblelinkerbychemoselectivecoupling.Thecovalentlyattachedpeptidesaredisplayedinfourcopiesoneachslide.Inaddition,multipleidenticalcopiesofeachmicroarrayareproduced.Incubationcanbeperformedmanuallyorautomatedusingonlyminimalamountsofyoursample.Read-outviafluorescenceresultsinlowbackgroundandhighsensitivity.

BenefitsofJPTsRepliTope™PeptideMicroarrays
-Gethundredsofidenticalmicroarraycopies
-Peptidesarefreeoftruncatedsequences
-Smallamountsofyourprecioussamplesareneededforincubation
-Applicabletoavarietyofbiologicalsamples(e.g.serum,plasma,antibody)
-Lowbackgroundonglasssurface
-Read-outviafluorescence

RepliTope™EBV(EBNA3b)

SelectedReferencesforJPTsPeptideMicroarrays
"StructureofGPN-loopGTPaseNpa3andImplicationsforRNAPolymeraseIIAssembly"
Niessertal.,MolCellBiol. (2015)-PMID:26711263
"ProtectiveEfficacyofAdenovirus-proteinVaccinesAgainstSIVChallengesinRhesusMonkeys"
Barouchetal.,Science(2015)-PMID:26138104
"IdentificationandCharacterizationofCommonBCellEpitopeinBovineLeukemiaVirusviaHigh-throughputPeptideScreeningSysteminInfectedCattle"
Baietal.,Retrovirology(2015)-PMID:26715158
"High-ThroughputMicroarrayIncubationsUsingMulti-WellChambers"
Zerwecketal.,MethodsMolBiol.(2015)-PMID:26490464
"PeptideMicroarraysforCoverageofSequenceDiversityinMonitoringtheBcellImmuneResponse(TECH2P.911)"
Castro,etal.,TheJournalofImmunology(2015)-PMID:n.a.
"AntibodiestoInfluenzaNucleoproteinCross-reactwithHumanHypocretinReceptor2"
Ahmedetal.,ScienceTranslationalMedicine(2015)-PMID:26136476
"SerumReactomeInducedbyBordetellaPertussisInfectionandPertussisVaccines:QualitativeDifferencesinSerumAntibodyRecognitionPatternsRevealedbyPeptideMicroarrayAnalysis"
Valentinietal.,BMCImmunol.(2015)-PMID:26129684

ApplicationNotes
"AModularApproachforEpitopeDiscoveryandHigh-ResolutionProfilingofHumoralImmuneResponses"
Pawlowskietal.(2013)Fulltext
"MultipleSclerosisandEpsteinBarrVirusInfection.AnEpitopeMappingStudy"
Reimeretal.(2014)Fulltext
"TheChallengeofAntigenSequenceDiversity:SolutionswithULTRAPeptideLibraries"
Pawlowskietal.(2015)Fulltext
"RapidMimotopeOptimizationforPharmacokineticAnalysisoftheNovelTherapeuticantibodyIMAB362"
Danescharetal.(2014)Fulltext

TestimonialsforJPTsPeptideMicroarrays
"Overthepastfiveyearsmyresearchteamhasbeenactiveinthedevelopmentofspecies-specificpeptidearrays.Ourabilitytoadvancethistechnologyintonewresearchareashasbeendependentonworkingwiththehighestqualityofarrays.Inthisregard,JPTscommitmenttoexcellencehasbeenacriticalfoundationforthesuccessofourresearchprogram.Ihavebeenconsistentlyimpressedwiththeircustomerservice,technicalexpertiseandprofessionalism.Whenitcomestopeptideworktherearenootheroptionsforourgroup,JPTisthebest."
ScottNapper,PhD,VaccineandInfectiousDiseaseOrganization(VIDO),UniversityofSaskatchewan,Canada

"TheRV144HIVtrialisconsideredasoneoffirstsuccessfulHIVvaccinetrials.IthasbecomeclearthattheV2loopofgp120isanimportantsiteforimmunogenicityandprotectionfromHIVinfection.TheuseofJPTsPepStar™microarraytechnologyhasbeenveryusefulforthecorrelationoftheclincialoutcomewithhumoralimmuneresponses.AshavethecyclicpeptidesbeenfromJPTtovalidatethesefindings!."
JeffCurrier,PhD,WalterReedArmyInstitute,Rockville,Maryland,USA

"WestudymodulationofdopaminergicneurotransmissonbyTAAR1andD2R.ThefunctionalinteractionofthetworeceptorsinthebrainsupportsTAAR1asatargetforthetreatmentofpsychiatricdisorderssuchasschizophreniaorbipolardisorder.Tomaptheepitopesofournewlygeneratedspecificanti-ratTAAR1antibodiesweusedJPTsPepStarTMpeptidemicroarrays.Thepeptidemicroarraysgreatlycontributedtooursuccessfulandrecentlypublishedstudy.WewereverysatisifiedwiththeexceptionalproductandservicedeliveredbyJPTPeptideTechnologiesaswellastheirscientificCustomerSupportwhichwasalwaysatourdisposal."
StefanObermüller,F.Hoffmann-LaRocheLtd.,RochePharmaResearchandEarlyDevelopment,Basel,Switzerland

RepliTope™EBV(EBNA3b)

TechnicalData:
ApplicationAntibodyepitopediscovery
Immunemonitoring
ProteinNameEpstein-Barrnuclearantigen(EBNA)
OrganismEpstein-Barrvirus(HHV-4)
Indication/TopicAutoimmunedisease
Burkittslymphoma
Hodgkinslymphoma
Nasopharyngealcarcinoma
Numberofpeptides234 

FurtherInformation:
Amount1peptidemicroarray(eachpeptideisdeposited3xpersubarray,4subarraysperslide)+dummyslideandspacers(neededformanualincubation)
SpecificationsPeptidescan(15merswith11aaoverlap)
DocumentationCDwithProtocol,Datasheet,gal-fileandgal-viewer
Swiss-ProtID
Q1HVG4
NCBIABB89244
SequenceMKKAWLSRAQQADAGGASGSEDPPDYGD
QGNVQQVGSDPISPAIGPFELSAASEDD
PQSGPVEENLDAAAREEEEPDEQEHNGG
DDPLEVHTRQPRFVDVNPTQAPVIQLVH
AVYDSMLQSDLRSLGSLFLEQNLNIEEF
IWMCMTVRHRCQAIRQKPLPIDKQRRWK
LLSPYRTWRMGYRTQTLNVNSFETGGDK
VHPLLVTATLGCEEGLRHAITYSAGIVQ
LPRMSDQNQKIETAFLMARRARSLSAER
YTLFFDLVSSGNTLYAIWIGLGTRNRVA
FVEFVGWLCKKDHTHIREWFRQCTGRPS
PSKPWMRAHPVAVPYDDPLTSEETDLAY
ARGLAMSIEAARLPDDPIIVEDDDESEE
IEDKCDKDEEESGTEDVTSIPQTLPHSP
TVYGRPSVFYRKPDTKSTKKCRAIVTDL
SIIKVIEDEHRKKKTARTEQPRAKPDSP
APTVVLRRPPTQKVTGPAGSLSVQAQLE
PWQPLSWPHETRVILHGPPTQGDQAHGS
MLDLLEKDDQHMEQQVMATLLPPEPHQP
RSGRRAPCVYTADLDIESDEPATSEPVL
DQLLPAPGLGPLAIQPLTSPTTSQLRSS
APSHAQTPWPVTHPSQTPGGPTTQSLAP
ETEAPRQWPMPLRPIPLHPLRMQPISFN
PAVRPTPHQPPQVEPTFYQSTWVKPPQQ
YQPQMGHIPYQPRPTGHSTMLRPQWAPT
TMQPPPRAPTPMPPPQGPPTAMQRPQGA
PTPMPPPQGPPTAMQRPRGAPTPMPPPQ
GPPTAMQLSPRALTGQKGPAKHILRQLL
TGGVKSGRPSLKFKAALERQAAAGLRPS
PGSGTGAKIVQAPVFYPPVLQPIQVMWQ
VGSSKAVAASTVTQAPTEYTGERRLGGP
MSPTDIPPSKRVKKKAYPERKTPHGGPS
HSSTVMWENVSQGQQQTLECGGTDKQER
NMLGMGDIAVSSPSSSETSNDE
ProteinLength(aa)946

新闻动态
行业前沿
技术文章
最新产品

188进口试剂采购网 www.188bio.cn -中国试剂网,试剂网,化学试剂网,国药试剂,抗体公司,试剂公司,试剂盒公司,苏州试剂公司,北京化学试剂公司,天津化学试剂,试剂商城,试剂代理,流式抗体 细胞库查询 sitemap