ChromogenixAntithrombin 10IUisforthedeterminationofHeparininplasma.Antithrombininconjunctionwithheparinelikesubstancesisapotentinhibitorofthrombin,factorXa,factorXlaandfactorlXa. AntithrombinispreparedfromhumanplasmaandpurifiedbyaffinitychromatographywithanHeparineSepharosegelaccordingtotheprotocolofMiller-Anderssonetal.(Thromb.Res.5,439-452,1974).
Forlaboratoryuseonly.
Lyophilizedpowderpreparedfromhumanplasmaafteraffinitychromatographyonheparin-Sepharosegel.ContainshumanalbuminasastABIlizer.
Thelyophilizedpowderisstableat2-8°Cuntiltheexpirydateprintedonthelabel.ThereconstitutedAntithrombinisstablefor1monthat2-8°Cor6monthsat-20°CwhenusedforthedeterminationofHeparin,accordingtothetestconditionsofChromogenixCoatest®Heparin.
SpecificActivity: Above6IU/mgAntithrombin.
Note:Thispreparationisnotastandard.
Chromogenixantithrombin canbeused foranti-FXachromogenicassayswhereadditionofexogenousantithrombinisdesired.
TheactivityofFXacanbemeasuredusingthefollowingchromogenicsubstrates:
SouthernBiotech/Goat Anti-Human Lambda-Alexa Fluor® 555/2070-32/1.0 mg
vectorlabs/Biotinylated Aleuria Aurantia Lectin (AAL)/B-1395/1 mg
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Mouse IgG)/PK-6102/1 kit
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Universal)/PK-6200/1 kit
vectorlabs/Unconjugated Musa Paradisiaca (Banana) Lectin (BanLec)/L-1410/5 mg
GiottoBiotech/Calmodulin N60D/5 mg/G02CLM60cn