CatalogueNumber: | AN00005 |
ProductName: | anti-15Lipoxygenase2antibody |
Form: | liquid |
Host: | Rabbit |
Clonity: | polyclonal |
Isotope: | IgG |
Storage: | PBSwith0.02%sodiumazideand50%glycerolpH7.3,-20â&BDquo;ƒfor24months(Avoidrepeatedfreeze/thawcycles.) |
Background: | Inhumans,thereare6functionallipoxygenasesgenes.Twoofthemencodeforarachidonicacid12-lipoxygenating(ALOX12,ALOX12B)andtwofor15-lipoxygenatingenzymes(ALOX15,ALOX15B).ALOX15Bhasbeendescribedasthemostabundant15-lipoxygenatingenzymespeciesinhumancarotidatheroscleroticlesionsandtobeassociatedwithcerebrovascularsymptoms.(PMID:24373925).ALOX15Bhas4?isoforms?producedby?alternativesplicingwiththeMWof76,67,69and73kDa.13073-1-APcanalsorecognizethemouseAlox8protein. |
Immunogen: | arachidonate15-lipoxygenase,typeB |
Synonyms: | ALOX15B;Arachidonate15-lipoxygenaseB,15-LOX-B,15-LOX-2,Arachidonate15-lipoxygenasetypeII,Linoleate13-lipoxygenase15-Lob |
CalculatedMW: | 76kDa |
Specificity: | Human,Mouse,Rat |
TestedApplication: | ELISA,WB,IHC,IF |
RecommendedDilution: | WB:1:200-1:2000;IHC:1:20-1:200 |
IHCDilution: | Immunohistochemistryofparaffin-embeddedhumanprostatecancerusingALOX15Bantibodyatdilutionof1:100 |
WBDilution: | MCF7cellsweresubjectedtoSDSPAGEfollowedbywesternblotwithALOX15Bantibodyatdilutionof1:600 |
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