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TRC/anti- 15 Lipoxygenase 2 antibody/100μg/AN00005-100μg

ProductDescription

CatalogueNumber:AN00005
ProductName:anti-15Lipoxygenase2antibody
Form:liquid
Host:Rabbit
Clonity:polyclonal
Isotope:IgG
Storage:PBSwith0.02%sodiumazideand50%glycerolpH7.3,-20â&BDquo;ƒfor24months(Avoidrepeatedfreeze/thawcycles.)
Background:Inhumans,thereare6functionallipoxygenasesgenes.Twoofthemencodeforarachidonicacid12-lipoxygenating(ALOX12,ALOX12B)andtwofor15-lipoxygenatingenzymes(ALOX15,ALOX15B).ALOX15Bhasbeendescribedasthemostabundant15-lipoxygenatingenzymespeciesinhumancarotidatheroscleroticlesionsandtobeassociatedwithcerebrovascularsymptoms.(PMID:24373925).ALOX15Bhas4?isoforms?producedby?alternativesplicingwiththeMWof76,67,69and73kDa.13073-1-APcanalsorecognizethemouseAlox8protein.
Immunogen:arachidonate15-lipoxygenase,typeB
Synonyms:ALOX15B;Arachidonate15-lipoxygenaseB,15-LOX-B,15-LOX-2,Arachidonate15-lipoxygenasetypeII,Linoleate13-lipoxygenase15-Lob
CalculatedMW:76kDa
Specificity:Human,Mouse,Rat
TestedApplication:ELISA,WB,IHC,IF
RecommendedDilution:WB:1:200-1:2000;IHC:1:20-1:200
IHCDilution:Immunohistochemistryofparaffin-embeddedhumanprostatecancerusingALOX15Bantibodyatdilutionof1:100
WBDilution:MCF7cellsweresubjectedtoSDSPAGEfollowedbywesternblotwithALOX15Bantibodyatdilutionof1:600
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