Avanti Polar Lipids/Npalmitoylglycine / 870817/1 x 50mg

Products:

Theacylamidesareafamilyofendogenouslipidsthatactaspotentmodulatorsofpainandinflammation.Thebestcharacterizedmembersofthisfamilyarethearachidonoylamides,whichincludesN-arachidonoylethanolamide(AEA;anandamide).N-palmitoylglycine(PalGly)containsa16-carbonsaturatedfattyacidthatisamide-linkedtoglycineandisstructurallysimilartothephospholipid-derivedN-acylethanolamines.Endogenouslyproducedinratskinandspinalcord,PalGlyispresentin100-foldgreateramountsinskinand3-foldgreaterinbraincomparedtoAEA.¹

 

¹Rimmerman,N.,Bradshaw,H.B.,Hughes,H.V.,Chen,J.S.,Hu,S.S.,McHugh,D.,Vefring,E.,Jahnsen,J.A.,Thompson,E.L.,Masuda,K.,Cravatt,B.F.,Burstein,S.,Vasko,M.R.,Prieto,A.L.,ODell,D.K.,Walker,J.M. (2008)N-palmitoylglycine,anovelendogenouslipidthatactsasamodulatorofcalciuminfluxandnitricoxideproductioninsensoryneurons.MolPharmacol74:213-224.

Data:

MolecularFormula

C₁₈H₃₅NO₃

PercentComposition

C68.97%,H11.25%,N4.47%,O15.31%

Purity

>99%

StABIlity

1Years

Storage

-20°C

CASNumber

2441-41-0
CASRegistryNumberisaRegisteredTrademarkoftheAmericanChemicalSociety

MolecularWeight

313.475

ExactMass

313.262

Synonyms

PalGly