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Bpsbioscience/Anti-GITR Antibody/79053-2/100 µg

HostSpecies:HEK293
MW:HeavyChain:51kDa,LightChain:26kDa
Tag(s):none
Clonality:Monoclonal
Isotype:IgG1
Description:
Anti-GITRrecombinanthumanantibodyrecognizingtheGITRLbindingregionofhumanGITR.Thisantibodyhasnotbeentestedforcross-reactivitywithanyotherspecies.
Synonym(s):
glucocorticoid-inducedTNF-relatedligand,AITRL,CD357L,tumornecrosisfactorligandsuperfamilymember18,TNFSF18
AssayConditions:
InhibitionofGITR:GITRLinteractionwithanti-GITRantibody(BPSBioscience,#79053)throughGITR:GITRLTR-FRETAssayKit(BPSBioscience#79054).DatainthegraphsareexpressedasFRETratios.
Formulation:
8mMNaPhosphatepH7.4,110mMNaCl,2.2mMKCland20%glycerol
Purification:
ProteinAaffinitychromatographyfromHEK293supernatants.
Storage/StABIlity:
Stableforatleast12monthsat-80°C.Avoidfreeze/thawcycles.Storedilutedantibodywithcarrierprotein(BSA0.1–0.5%)at4°C,stablefor2weeks.
Application(s):
UsefulforinhibitionofGITR:GITRLinteraction.
Reference(s):
1.Cohen,A.,etal.,CancerResearch.2006May;66(9):4904-4912.

2.Scumpia,P.O.,etal.,Blood.2007Oct;110(10):3673-3681.

ScientificCategory:
Immunotherapy
ProductType:
Antibody
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