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Accelagen/PAK7KD (recombinant human PAK7 kinase domain, aka PAK5)/K0108B/ Bulk

Description:
HumanPAK7kinase(UniProt:Q9P286;NCBI:NM_177990)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesareregulatedbythesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.PAK7(PAK5)ispredominantlyexpressedinbrain.Itiscapableofpromotingneuriteoutgrowthandcellsurvival.PAK7KD(PAK5KD)isarecombinantwildtypehumanPAK7kinasedomain(aminoacids425–719offull-lengthhumanPAK7)expressedinE.coliandpurifiedtohomogeneitywithfullactivity.

MolecularMassandPhosphorylation:
Thecalculatedmassis33,934.PAK7KDisfullyphosphorylatedatS602andanadditionalsitewithameasuredmassof34,096(2P).

StABIlityandStorage:
Stableat-70oCfor12monthsfromdateofreceipt.Proteinshouldbethawedonice.Proteincanbeflash-frozeninliquidnitrogenandstoredat-70oC.

Applications:
Enzymaticstudies,inhibitorscreen,andselectivityprofiling
Highconcentrationavailableforcrystallization

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