Description | Celldivisioncontrolprotein6homolog(CDC6)isthehumanhomologofSaccharomycescerevisiaeCDC6.ThisproteinfunctionsasaregulatorintheearlystepsofDNAreplicationandalsohasaroleincheckpointcontrolsthatensurethatDNAreplicationiscompletedbeforeinitiationofmitosis. |
BatchNo. | Seeproductlabel |
Unitsize | 100µg |
Antigen | RecombinanthumanCelldivisioncontrolprotein6homolog(CDC6) |
Clone | IMD-6 |
OtherNames | CDC6-relatedprotein;p62(cdc6);HsCDC6;HsCDC18;CDC6;CDC18L; |
Accession | Q99741CDC6_HUMAN; |
Producedin | Mouse |
Purity | IgG |
Applications | WesternBlotting(WB).Aconcentrationof1.0-2.0µg/mlisrecommendedforWB.HumanCDC6hasapredictedlengthof560residuesandMWof63kDa.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBagainsttheantigen. |
Cross-reactivity | Human; |
Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample. |
Form | Lyophilizedfrom1.2%sodiumacetate,2mgBSA,0.01mgNaN3 |
Reconstitution | Reconstitutein1mlofPBS(pH7.4)toachieveanantibodyconcentrationof100µg/ml.Centrifugetoremoveanyinsolublematerial. |
Storage | Atleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles |
ExpiryDate | 12monthsafterpurchase |
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