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| Description | Cyclin-dependentkinase7(CDK7)belongstothecyclin-dependentproteinkinasefamily.CDK7associateswithcyclinHandMAT1toformthetrimericCDK-activatingkinase(CAK)complex.CAKactivatescyclin-associatedkinasessuchasCDK4andCDK6bythreoninephosphorylation. |
| BatchNo. | Seeproductlabel |
| Unitsize | 100µg |
| Antigen | RecombinanthumanCyclin-dependentkinase7(CDK7) |
| Clone | IMD-26 |
| OtherNames | Celldivisionproteinkinase7;CDK-activatingkinase;CAK;CAK1;TFIIHbasaltranscriptionfactorcomplexkinasesubunit;39kDaproteinkinase;P39Mo15;STK1;CDK7;MO15;CDKN7;SerinethreoninekinaseStk1; |
| Accession | P50613CDK7_HUMAN; |
| Producedin | Mouse |
| Purity | IgG |
| Applications | Immunohistochemistry(IHC)andWesternBlotting(WB).Aconcentrationof0.25µg/mlisrecommendedforWB.HumanCDK7hasapredictedlengthof346residuesandMWof39kDa.Aconcentrationof0.5µg/mlisrecommendedtodetecttheproteininformalin/acetonefixedfrozentissues.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen. |
| Cross-reactivity | Human; |
| Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample. |
| Form | Lyophilizedfrom1.2%sodiumacetate,2mgBSA,0.01mgNaN3 |
| Reconstitution | Reconstitutein1mlofPBS(pH7.4)toachieveanantibodyconcentrationof100µg/ml.Centrifugetoremoveanyinsolublematerial. |
| Storage | Atleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles |
| ExpiryDate | 12monthsafterpurchase |
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