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Biosensis/Mouse Monoclonal antibody to human JAG1 [1E12]/M-800-200/200 µl188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Biosensis/Mouse Monoclonal antibody to human JAG1 [1E12]/M-800-200/200 µl

DescriptionThejagged1proteinencodedbyJAG1isthehumanhomologoftheDrosophiliajaggedprotein.Humanjagged1istheligandformultipleNotchreceptorsinvolvedinthemediationofNotchsignalling.Itmaybeinvolvedincell-fatedecisionduringhematopoiesisandseemstobeinvolvedinearlyandlatestagesofmammaliancardiovasculardevelopment.JAG1isatransmembraneproteinthatiswidelyexpressedinadultandfetaltissues.Mutationsthatalterthejagged1proteincauseAlagillesyndromewhichisanautosomaldominantmultisysstemdisorder.DefectsinJAG1arealsothecauseoftetralogyofFallot(TOF)whichisacongenitalheartanomaly.
BatchNo.Seeproductlabel
Unitsize200µl
AntigenPartialrecombinanthumanJAG1(aminoacids531-621)withaGSTtag
Clone[1E12]
OtherNamesProteinjagged-1;Jagged1;hJ1;CD339antigen;JAG1;JAGL1;
AccessionJAG1_HUMAN
ProducedinMouse
PurityAscitesfluid
ApplicationsThisantibodyisrecommendedfordirectELISAandWB.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificitySpecificitywasdemonstratedbyWBagainsttheantigen.
Cross-reactivityHuman.Otherspeciesnotyettested.
BlastitToseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit.
FormLyophilised
ReconstitutionReconstitutein200µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforhigherstABIlityorat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchase
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