Everest Biotech/Erlotinib HCl 1g/1100150013/1g

MaterialSafetyDataSheet

Date:Oct23,2015

1.PRODUCTANDCOMPANYIDENTIFICATION

1.1Productidentifier

Productname:ErlotinibHCl

CatalogNo:1100150013,1100150023,1100150053,1100150103,1100150253

1.2Relevantidentifiedusesofthesubstanceormixtureandusesadvisedagainst

Forresearchuseonly.

1.3Detailsofthesupplierofthesafetydatasheet

Company:EtonBioscienceInc

TollFree:1-800-758-1630

Tel:1-800-758-1630

Fax:1-800-507-2912

1.4Emergencytelephonenumber

1-800-758-1630

2.HAZARDSIDENTIFICATION

2.1Classificationofthesubstanceormixture

Acutetoxicity:oral,Category4

Acutetoxicity:dermal,Categort4

Acutetoxicity:inhalation(Dusts/Mists),Category4

Skincorrosion/irritation,Category2

Seriouseyedamage/eyeirritation,Category2A

Specifictargetorgantoxicity,Category3

2.2GHSLabelelements,includingprecautionarystatements

Pictogram

MolecularWeight:	429.9g/mol
MolecularFormula:	C22H23N3O4•HCl
CASNumber:	183319-69-9
Solubility:	SolubleinDMSOat18mg/mLwithwarming;verypoorlysolubleinethanol
Purity:	≥99%
Storage:	-20C
Applications:	Anti-neoplastic

SignalWord PrecautionaryStatement P264 P301+P312 P501

Warning Washskinthoroughlyafterhandling IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell. Disposeofcontents/containertoanapprovedwastedisposalplant

2.3Otherhazards

None

3.COMPOSITION/INFORMATIONONINGREDIENTS

3.1Substances

MolecularFormula:C₂₉H₃₁N₇O.CH₄SO₃

MolecularWeight:429.9g/mol

CASNo:183319-69-9

4.FIRSTAIDMEASURES

4.1Descriptionoffirstaidmeasures

Eyecontact

Checkforandremovecontactlensesandflushwithcopiousamountsofwater;assureadequateflushingbyseparatingtheeyelidswithfingers;callaphysician

SkinContact

Flushwithcopiousamountsofwater;removecontaminatedclothingandshoes;callaphysician

Inhalation

Ifinhaled,removetofreshair;ifbreathingisdifficult,giveoxygen;ifbreathingstops,giveartificialrespiration

Ingestion

Ifswallowed,washoutmouthwithcopiousamountsofwater;callaphysician

4.2Mostimportantsymptomsandeffects,bothacuteanddelayed

Noinformationavailable

4.3Indicationofanyimmediatemedicalattentionandspecialtreatmentneeded.

Noinformationavailable

5.FIREFIGHTINGMEASURES

5.1Extinguishingmedia

Suitableextinguishingmedia

Waterspray,carbondioxide,drychemicalpowderorfoam

5.2Specialhazardsarisingfromthesubstanceormixture

Noinformationavailable

5.3Adviceforfirefighters

Wearself-containedbreathingapparatusandprotectiveclothingtopreventcontactwithskinandeyes.

6.ACCIDENTALRELEASEMEASURES

6.1Personalprecautions,protectiveequipmentandemergencyprocedures

Usefullpersonalprotectiveequipment.Evacuatepersonneltosafeareas.

6.2Environmentalprecautions

Preventfurtherleakageorspillage.Preventproductfromenteringdrain.

6.3Methodsandmaterialforcontainmentandcleaningup

Absorbsolutionswithfinely-powderedliquid-bindingmaterial(diatomite,universalbinders);decontaminatesurfacesandequipmentbyscrubbingwithalcohol;disposeofcontaminatedmaterialaccordingtoSection13

7.HANDLINGANDSTORAGE

7.1Precautionsforsafehandling

Avoidskin/eyecontact.Useprotectiveequipmentasneeded.Washcontaminatedclothingbeforereuse.

7.2Conditionsforsafestorage,includinganyincompatibilities

Keepcontainertightlyclosedinacool,well-ventedplace.Storeat-20˚C.

7.3Specificenduse(s)

Nodataavailable.

8.EXPOSURECONTROLS/PERSONALINFORMATION

8.1ControlParameters

Thisproductcontainsnohazardousmaterialswithoccupationalexposurelimits.

8.2Exposurecontrols

Engineeringcontrols

Provideshowerandeyewashstation

Personalprotectiveequipment

9.PHYSICALANDCHEMICALPROPERTIES

9.1Informationonbasicphysicalandchemicalproperties

9.2Othersafetyinformation

Nodataavailable.

10.STABILITYANDREACTIVITY

10.1Reactivity

Nodataavailable

10.2Chemicalstability

Stableunderrecommendedstorageconditions.

10.3Possibilityofhazardousreactions

Nodataavailable.

10.4Conditionstoavoid

Protectfromlightandheat

10.5IncompatIBLematerials

strongoxidizingagents

10.6Hazardousdecompositionproducts

Thermaldecompositionmayproducetoxicgasessuchascarbonmonoxide,carbondioxide,andnitrogenoxides

11.TOXICOLOGICALINFORMATION

11.1Informationontoxicologicaleffects

Toxicologicaleffectsonthisproducthavenotbeenthoroughlystudied.

12.ECOLOGICALINFORMATION

12.1Toxicity

Avoidreleaseintoenvironment

12.2Persistenceanddegradability

Nodataavailable

12.3.Bioaccumulativepotential

Nodataavailable

12.4Mobilityinsoil

Nodataavailable

12.5ResultsofPBTandvPvBassessment

Nodataavailable

12.6Otheradverseeffects

Nodataavailable

13.DISPOSALINFORMATION

13.1Wastetreatmentmethods

Disposeinaccordancewithlocal,state,andfederalregulations.

14.TRANSPORTINFORMATION

DOT:
Propershippingname:none
Non-Hazardousfortransport:thissubstanceisconsideredtobenon-hazardousfortransport
IATA:
Propershippingname:none
Non-Hazardousfortransport:thissubstanceisconsideredtobenon-hazardousfortransport

IMDG:
Propershippingname:none
Non-Hazardousfortransport:thissubstanceisconsideredtobenon-hazardousfortransport

15.REGULATORYINFORMATION

EURiskandSafetyphrases:

R22:Harmfulifswallowed

S22:Donotbreathedust

S24/25:Avoidcontactwithskinandeyes

S26:Incaseofcontactwitheyes,rinseimmediatelywithplentyofwaterandseekmedicaladvice

S28:aftercontactwithskin,washimmediatelywithplentyofwater

S36/37/39:Wearsuitableprotectiveclothing,glovesandeye/faceprotection

16.OTHERINFORMATION