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Hello Bio/DAMGO/HB2409/10mg

Productoverview

  • Name
    DAMGO
  • Shortdescription
    Potent,selectiveμ-opioidreceptoragoNIST
  • BIOLOGicaldescription
    Potent,selectiveμ-opioidreceptoragonist(Kivaluesare2.0and>1000nMatμ,κandδrespectively).Showsantinociceptiveactivity.
  • Alternativenames
    DAGO
  • Biologicalaction
    Agonist
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    H-Tyr-D-Ala-Gly-N(Me)Phe-Gly-ol
  • MolecularWeight
    513.7
  • MolecularFormula
    C26H35N5O6
  • CASNumber
    78123-71-4
  • PubChemidentifier
    5462471
  • SMILES
    C[C@H](C(=O)NCC(=O)N(C)[C@@H](CC1=CC=CC=C1)C(=O)NCCO)NC(=O)[C@H](CC2=CC=C(C=C2)O)N
  • InChi
    InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1
  • InChiKey
    HPZJMUBDEAMBFI-WTNAPCKOSA-N
  • MDLnumber
    MFCD00133215

StoringandUsingYourProduct

  • Storageinstructions
    -20°C(desiccate)
  • Solubilityoverview
    Solubleinwater(4mM)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforDAMGO

  • Pharmacologicalcharacterizationoftheclonedkappa-,delta-,andmu-opioidreceptors.

    Raynoretal(1994)MolPharmacol45(2):330-4
    PubMedID:8114680

  • Theμ-opioidreceptoragonistDAMGOpresynapticallysuppressessolitarytract-evokedinputtoneuronsintherostralsolitarynucleus.

    Boxwelletal(2013)JNeurophysiol109(11):2815-26
    PubMedID:23486207

  • DAMGOinthecentralamygdalaalleviatestheaffectivedimensionofpaininaratmodelofinflammatoryhyperalgesia.

    Zhangetal(2013)Neuroscience252:359-66
    PubMedID:23994597
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