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Hello Bio/Wortmannin/HB2778/5mg

Productoverview

  • Name
    Wortmannin
  • Shortdescription
    Potent,selective,irreversIBLePI3-Kinhibitor
  • BIOLOGicaldescription
    Potent,selective,non-compettiveandirreversiblePI3-Kinhibitor(IC50=2-4nM).AlsoinhibitsPI3-KrelatedkinasesandPLK1.Cellpermeable.Showsvarietyofbiologicalactions.
  • Alternativenames
    SL-2052
  • Biologicalaction
    Inhibitor
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    (1S,6bR,9aS,11R,11bR)11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5,-h]-2-h]-2-benzopyran-3,6,9-trione
  • MolecularWeight
    428.44
  • MolecularFormula
    C23H24O8
  • CASNumber
    19545-26-7

StoringandUsingYourProduct

  • Storageinstructions
    -20°C(desiccate)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforWortmannin

  • Wortmanninasauniqueprobeforanintracellularsignallingprotein,phosphoinositide3-kinase.

    Uietal(1995)TrendsBiochemSci20(8):303-7
    PubMedID:7667888
  • Wortmannin,apotentandselectiveinhibitorofphosphatidylinositol-3-kinase.

    Powisetal(1994)CancerRes54(9):2419-23
    PubMedID:8162590
  • Wortmannin,awidelyusedphosphoinositide3-kinaseinhibitor,alsopotentlyinhibitsmammalianpolo-likekinase.

    Liuetal(2005)ChemBiol12(1):99-107
    PubMedID:15664519
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