Thisproductconsistsoftheimmunoglobulinfractionofrabbitanti-S-100serum.TheantibodywasgeneratedinrabbitsagainstS-100proteinisolatedfrombovinebrain.
Commondeterminantsonthisproteinoccuramongstwidelydisparatespecies,e.g.fruitflyandman.Anti-S-100reactswiththealphaandbetasubunitsofS-100A.Inthecentralnervoussystem,glialandependymalcellsstainpositively.Intheperipheralnervoussystem,Schwanncellsarepositivelylabeled.MelanocytesandLangerhanscellsstaininskin.
PhotoDescription:IHCimageofahumanastrocytomastainingfors-100beta.Thetissuewasformalinfixedandembeddedinparaffin,beforemicrotomesectioningandantigenretrieval.SectionswereincubatedatRTin10%goatseruminPBS,beforestandardIHCprocedure.Primaryantibodywasincubatedat1:5000for48hours,goatanti-rabbitsecondarywassubsequentlyaddedfor1hourafterwashingwithPBS.Lightmicroscopystainingwasachievedwithstandardbiotin-streptavidin/HRPprocedureandDABchromogen.
Host: Rabbit
Quantity/Volume: 6mL
State: Liquid
ReactsWith:Bullfrog,Ferret,Fish,Gerbil,Human,Monkey,Mouse,Rat
AvailABIlity:InStock
AlternateNames: S-100proteinalphachain;S-100proteinsubunitalpha;S100alpha;S100calcium-bindingproteinA1;S100A;S100calciumbindingproteinA1,anti-S100
GeneSymbol/ID,Accession#: S100A1,528735
RRID: AB_572261
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