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LifeSensors/UB208H- .8 NMOLES UBE2R1 (CDC34), His6/UB208H- .8 NMOLES UBE2R1 (CDC34), His6

236 amino acid product of the CDC34 gene. It controls cellular proliferation through regulation of p27/Kip1 protein levels. Blocking CDC34 activity enhances the anti-myeloma effects of Bortezomib.


Info

Amount0.8 nmol
StateLiquid
Molecular Weight27,730.8 Da
SourceHuman Recombinant
Fusion TagHis6
Accession NumberP62837
Alternate NamesUBC3, E2-CDC34, UbcH3
Storage-80°C, avoid freeze/thaw cycles
Stability1 year under recommended storage conditions
Recommended UseEnzyme concentration of 100 nM – 1 mM is recommended for in vitro conjugation.



Applications
  • Identify cognate E2/E3 pairs
  • Characterize upregulation/downregulation of E2 enzymes
  • Build poly-ubiquitin chains
  • Characterize ubiquitin chain specificity of E2 enzymes
  • Analyze expression of E2 enzymes


Benefits
  • Untagged (native) E2 conjugation enzyme


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