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Neuromics/CD4/MO20025/100 ul

Type:MouseIgG

 

Applications:IHC

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:H

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:Supernatant-liquid

 

Immunogen:ProkaryoticrecombinantproteincorrespondingtotheexternaldomainofthehumanCD4molecule.Clone:1F6

 

Picture

CD4isasinglechaintransmembraneousglycoprotein(59kDa)whichbelongstotheimmunoglobulinsuperfamily.TheCD4antigenisexpressedonaTcellsubset(helper/inducer)representing45percentofperipheralbloodlymphocytesandatalowerlevelonmonocytes.MostcasesofcutaneousTcelllymphoma,includingmycosisfungoides,expresstheCD4antigenandHTLV-1associatedadultTcellleukemia/lymphomaisalsogenerallyCD4positive.

Note:theuseof1percentorgreaterH2O2toblockendogenousperoxidasehasadetrimentaleffectontheepitoperecognizedbyclone1F6.Therefore,itisrecommendedthatendogenousperoxidaseisblockedbeforeretrievalwith0.5percentH2O2/methanolfor10minutes,otherwisestainingintensitymaybereduced

Image:CD4stainingof  Humanskin,mycosisfungoides.NotemembranestainingofinfiltratingTlymphocytes.Paraffinsection.

MoreLinks:

CDandCellSurfaceMarkerAntibodies

CDandCellSurfaceProteins

ImmuneResponseResearchAntibodies                               

ImmuneResponseResearchProteins

CancerResearchAntibodies     

CancerResearchProteins                                          

StemCellResearchReagents

Neuronal-GlialMarkers-Astrocytes,Glia,Microglia,Olidogodendrocytes,ProgenitorsandSchwannCellMarkers

 

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