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Neuromics/Macrophage Scavenger Receptor I/CD204/RA25074/100 ul

Type:RabbitIgG

 

Applications:ICC;IHC;WB

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:B;Ca;H;M;Pr;R

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

 

Immunogen:Syntheticpeptidemadetoaninternalportionofthehumanprotein(withinresidues400-450).[Swiss-Prot#P21757]

 

Picture

Macrophagescavengerreceptors(MSR)aremembraneglycoproteinsthatmediatetherecognitionanduptakeofavarietyofmacromolecules,includingmodifiedlipoproteins,advancedglycationend(AGEs)productsandamyloidb-protein(Abeta).WhilethenormalroleofMSRisassociatedwithcelladhesionandhostdefensemechanisms,italsohasbeenimplicatedinthedevelopmentofatherosclerosisandAbetadepositioninAlzheimer"sdisease(AD).

Image:MSRIstaining(green)inHelacellsata1:50dilution.Nuclei(Blue)arecounterstainedusingHoechst33258.

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