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Renin is a secreted aspartyl protease that plays a crucial role in the regulation of blood pressure and salt balance through the cleavage of angiotensinogen, the only known physiological substrate of Renin. Renin is expressed as a precursor consisting of a signal sequence (aa 1 - 23), a propeptide (aa 24 - 66), and a mature chain (aa 67 - 406). The amino acid sequence of human REN is 100%, 73%, 71% and 67% identical to that of chimpanzee, canine, mouse and rat.
Image: Renin Propeptide was detected in paraffin-embedded human kidney glomerulus sections using 15 µg/ml mouse anti-human Renin monoclonal antibody. Tissue was subjected to antigen retrieval, stained using anti-mouse HRP-DAB (brown), and counterstained with hematoxylin (blue).
SouthernBiotech/Goat Anti-Human Lambda-Alexa Fluor® 555/2070-32/1.0 mg
vectorlabs/Biotinylated Aleuria Aurantia Lectin (AAL)/B-1395/1 mg
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Mouse IgG)/PK-6102/1 kit
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Universal)/PK-6200/1 kit
vectorlabs/Unconjugated Musa Paradisiaca (Banana) Lectin (BanLec)/L-1410/5 mg
GiottoBiotech/Calmodulin N60D/5 mg/G02CLM60cn