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Productoverview

  • Name
    GeNISTein
  • Shortdescription
    ProteintyrosinekinaseinhibitorandPPARγagonist.Phytoestrogen.
  • BIOLOGicaldescription
    Phytoestrogen.ProteintyrosineinhibitorandPPARγandPPARαagonist(Kivalues=5.7nMatPPARγ).Alsobindsestrogenreceptorstoexertweakestrogenicactivity.Showsvarietyofbiologicalactions.
  • Biologicalaction
    Agonist
  • Purity
    >98%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • MolecularWeight
    270.24
  • Chemicalstructure
    Genistein
  • MolecularFormula
    C15H10O5
  • CASNumber
    446-72-0

StoringandUsingYourProduct

  • Storageinstructions
    -20°C(desiccate)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforGenistein

  • Genistein,aspecificinhibitoroftyrosine-specificproteinkinases.

    AkiyamaTetal(1987)JBiolChem262(12):5592-5.
    PubMedID:3106339

  • Naturalproductagonistsofperoxisomeproliferator-activatedreceptorgamma(PPARγ):areview.

    WangLetal(2014)BiochemPharmacol92(1):73-89.
    PubMedID:25083916

  • Genisteinincreasesepidermalgrowthfactorreceptorsignalingandpromotestumorprogressioninadvancedhumanprostatecancer.

    NakamuraHetal(2011)PLoSOne6(5):e20034.
    PubMedID:21603581

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