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QED Bioscience/Telomerase Catalytic Subunit/34025/1 Ea


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TelomeraseCatalyticSubunitMonoclonalAntibody


ORDERINGINFORMATION

CatalogNo.:34025

Size:50ulascitesfluidcontaining0.05%sodiumazide.Antibodyconcentrationapprox.0.9mg/ml.


BACKGROUND

Telomeraseisareversetranscriptasethataddstelomericrepeats(TTAGGG)tochromosomeends.Innormalsomaticcells,telomeraseisnotactiveandtelomeresprogressivelyshorten,leADIngtolimitedcellLifespanandsenescence.Activationoftelomeraseisassociatedwithhumancancersandcellimmortalization.Humantelomeraseiscomprisedofthreemajorsubnunits:acatalyticsubunit(hTERT),atemplateRNA(hTR),andtelomerase-associatedprotein(TEP-1).TranscriptionofTERTistheprimarymechanismforregulatingtelomeraseactivity.


SPECIFICATIONSUMMARY

Antigen:Full-lengthrecombinanthTERTexpressedininsectcells.HostSpecies:Mouse

CloneNo.:2C4

AntibodyClass:IgM

Preservatives:0.05%sodiumazide


SPECIFICITY

ThisantibodyrecognizeshumanTERT;specificepitopenotdetermined.

APPLICATIONS

Immunoblotting:Useat1:500-1:1,000dilution.

Flowcytometry:Useat1:400dilution.Immunohistochemistry:Useat1:1,000dilution.

Pancreas:Formalin-fixed,paraffin-embedded


DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableat4oC(short-term)and-70oC(long-term).

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.


QEDBioscience,Inc.10919TechnologyPlace,SuiteC

SanDiego,CA92127

TollFree800.929.2114

Phone858.675.2405

Fax858.592.1509

info@qedbio.com

Visitourwebsiteforadditionalproductinformationandtoorderonline.

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