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QED Bioscience/Telomerase-Associated Protein 1/34026/1 Ea


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Telomerase-AssociatedProtein-1PolyclonalAntibody


ORDERINGINFORMATION

CatalogNo.:34026

Size:50ugimmunogenaffinitypurifiedantibodyinPBScontaining0.02%sodiumazide.


BACKGROUND

Telomeraseisareversetranscriptasethataddstelomericrepeats(TTAGGG)tochromosomeends.Innormalsomaticcells,telomeraseisnotactiveandtelomeresprogressivelyshorten,leADIngtolimitedcellLifespanandsenescence.Activationoftelomeraseisassociatedwithhumancancersandcellimmortalization.Humantelomeraseiscomprisedofthreemajorsubnunits:acatalyticsubunit(hTERT),atemplateRNA(hTR),andtelomerase-associatedprotein(TEP-1).TranscriptionofTERTistheprimarymechanismforregulatingtelomeraseactivity.


SPECIFICATIONSUMMARY

Antigen:SyntheticpeptideconjugatedtoKLH

HostSpecies:Rabbit

Preservatives:0.02%sodiumazide


SPECIFICITY

Thisantibodyrecognizesanepitopewithin20aminoacidsneartheaminoterminusofhumanTEP-1.


APPLICATIONS

Immunoblotting:Useat5ug/ml.

Immunohistochemistry:Useat5ug/ml.

Skin:Formalin-fixed,paraffin-embedded

Breast:Formalin-fixed,paraffin-embedded


DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.


STORAGEANDSTABILITY

Thisantibodyisstableat4oC(short-term)and-70oC(long-term).


Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

QEDBioscience,Inc.10919TechnologyPlace,SuiteC

SanDiego,CA92127

TollFree800.929.2114

Phone858.675.2405

Fax858.592.1509

info@qedbio.com

Visitourwebsiteforadditionalproductinformationandtoorderonline.

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