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TOKU-E/Thiamphenicol/T005/1 g

Thiamphenicolisabacteriostaticantibioticderivedfromchloramphenicol.Likechloramphenicol,thiamphenicolisinsolubleinwaterbuthighlysolubleinlipids.

    CASNumber

    15318-45-3

    MolecularFormula

    C12H15Cl2NO5S

    MolecularWeight

    356.22g/mol

    MechanismofAction

    Boththiamphenicolandchloramphenicolworkbythesamemechanism,however,thiamphenicolisabout3Xaspotent.Afterenteringabacterialcell,thiamphenicolbindstothe50Sribosomalsubunitpreventingpeptidebondformation.ResistancetothiamphenicolmaybeduetodecreasedcellpermeABIlityoramutationinthe50Sribosomalsubunit.

    StorageConditions

    2-8°C,protectfromlight

    TariffCode

    2941.40.0000

    Spectrum

    ThiamphenicolisabroadspectrumantibioticcommonlyusedtotargetbacteriaresponsIBLeforcausingsexuallytransmitteddiseases.

Specifications:

    Form

    Powder

    Appearance

    Off-whitepowder

    Source

    Synthetic

    Absorbance

    UVmax(95%ethanol):224,266,274nm(ε13,700,800,700).

    MeltingPoint

    164.3-166.3°C

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