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The L17F12 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is a member of the scavenger receptor superfamily and is present on approximately 70% of normal peripheral blood lymphocytes. CD5 is involved in modulating antigen receptor signaling in both T and B cells and acts through binding of CD72, its receptor expressed on B cells.
| Name | APC Anti-Human CD5 (L17F12) |
|---|---|
| Cat. No. | 20-0058 |
| Alternative Names | Leu-1, T1 |
| Gene ID | 921 |
| Clone | L17F12 |
| Isotype | Mouse IgG2a, kappa |
| Reactivity | Human |
| Cross Reactivity | No |
| Format | APC |
| Applications | Flow Cytometry |
| Citations* | Knapp W, Dorken B, et al. eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. Gadol N and Ault KA. 1986. Immunol Rev. 93: 23-34. Antin JH, Emerson SG, Martin P, Gadol N and Ault KA. 1986. J Immunol. 136: 505-510. Raab M, Yamamoto M and Rudd CE. 1994. Mol Cell Biol. 14(5): 2862-2870. Lydyard PM, Lamour A, MacKenzie LE, Jamin C, Magged RA and Youinou P. 1993. Immunol Lett. 38(2): 159-166. McKenna RW, Washington LT, Aquino DB, Picker LJ and Kroft SH. 2001. Blood. 98(8): 2498-2507. (Flow Cytometry) Butmarc JR, Kourea HP, Levi E and Kadin ME. 1998. Am J Clin Path. 109(6): 682-688. (Immunohistochemistry - paraffin-embedded tissue) |
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