The HIT2 antibody is specific for human CD38, a 45 kD type II transmembrane glycoprotein expressed on thymocytes, activated T and B cells, and monocytes as well as other non-hematopoietic cells. CD38 is an ectoenzyme that functions to catalyze the synthesis and hydrolysis of cyclic ADP-ribose and is involved in cell signaling, regulating cell adhesion, and activation. Additionally, CD38 has been shown to be a prognostic marker for some leukemias and other diseases.
Name | PE Anti-Human CD38 (HIT2) |
---|---|
Cat. No. | 50-0389 |
Alternative Names | No |
Gene ID | No |
Clone | HIT2 |
Isotype | Mouse IgG1, kappa |
Reactivity | Human |
Cross Reactivity | No |
Format | PE |
Applications | Flow Cytometry |
Citations* | Dianzani U, and Malavasi F. 1995. Crit. Rev. Immunol. 15(2):167-200. Mehta K, Shahid U, and Malavasi F. Oct. 1996. FASEB J. 10(12):1408-1417. Ferrero E, and Malavas F. Feb. 1999. J. Jeukoc. Biol. 65(2):151-161. Matrai Z. Feb. 2005. Hematology. 10(1):39-46. |
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