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Adipogen/β-Rubromycin/BVT-0251-M001/1 mg

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ProductDetails
SynonymsMethyl-8,10"-dihydroxy-5,7-dimethoxy-4,9,9"-trioxo-4,4",9,9"-tetrahydro-3H,3"H-spiro[naphtho[2,3-b]furan-2,2"-pyrano[4,3-g]chromene]-7"-carboxylate
ProductTypeChemical
Properties
FormulaC27H20O12
MW536.4
CAS27267-70-5
Source/HostChemicalsIsolatedfromStreptomycessp.
PurityChemicals≥98%(HPLC)
AppearanceDarkbluesolid.
SolubilitySolubleinDMSOorchloroform.
IdentityDeterminedby1H-NMR.
DeclarationManufacturedbyBioViotica.
InChiKeyYYQMDOZKNSEHDS-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Afterreconstitutionprotectfromlightat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Antibiotic.
  • HIV-1reversetranscriptaseinhibitor.
  • Humantelomeraseinhibitor.
  • Cytostaticagainstdifferenttumorcelllines.
ProductReferences
  1. Thestructureofrubromycin:H.Brockmann,etal.;THL30,3525(1966)
  2. RubromycinII:H.Brockmann,etal.;Chem.Ber.102,126(1969)
  3. Rubromycins.3.Theconstitutionofalpha-rubromycin,beta-rubromycin,gamma-rubromycin,andgamma-iso-rubromycin:H.Brockmann&A.Zeeck;Chem.Ber.103,1709(1970)
  4. Inhibitionofhumanimmunodeficiencyvirus-1reversetranscriptaseactivitybyrubromycins:competitiveinteractionatthetemplate.primersite:M.E.Goldman,etal.;Mol.Pharmacol.38,20(1990)
  5. Inhibitionofhumantelomerasebyrubromycins:implicationofspiroketalsystemofthecompoundsasanactivemoiety:T.Ueno,etal.;Biochemistry39,5995(2000)
  6. Structuralandbiosyntheticinvestigationsoftherubromycins:C.Puder,etal.;Eur.J.Org.Chem.2000,729(2000)
  7. Determinationoftheabsoluteconfigurationsofgamma-rubromycinsandrelatedspirocompounds:G.Bringmann,et.al.;Eur.J.Org.Chem.2000,2729(2000)
  8. Rubromycins:Structurallyintriguing,BIOLOGicallyvaluable,syntheticallychallengingantitumourantibiotics:M.Brasholz,etal.;Eur.J.Org.Chem.2007,3801(2007)
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