Deprecated: Required parameter $cat_id follows optional parameter $type in /www/wwwroot/ebimall.com/systems/hong.php on line 2088

Deprecated: Required parameter $where follows optional parameter $tree_id in /www/wwwroot/ebimall.com/systems/hlb.php on line 3505
AntibodiesOnline/Chemokine (CC Motif) Ligand 5 (CCL5) (AA 2491), (full length) protein (His tag)/188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
您好,欢迎您进入188进口试剂采购网网站! 服务热线:4000-520-616
蚂蚁淘商城 | 现货促销 | 科研狗 | 生物在线

AntibodiesOnline/Chemokine (CC Motif) Ligand 5 (CCL5) (AA 2491), (full length) protein (His tag)/
ProteinName
Chemokine(C-CMotif)Ligand5(CCL5)
  • Rantes
  • Scya5
  • D17S136E
  • RANTES
  • SCYA5
  • SIS-delta
  • SISd
  • TCP228
  • eoCP
  • MuRantes
  • chemokine(C-Cmotif)ligand5
  • LOC100230935
  • CCL5
  • Ccl5
ProteinCharacteristics
AA24-91,fulllength
36AA24-91
2AA1-91
2AA25-92
2fulllength
1AA1-50
1AA24-92
1AA26-91
1AA27-91
1partial
Origin
Human
66Human
20Mouse(Murine)
12Rat(Rattus)
3Cow(Bovine)
3GuineaPig
2Dog(Canine)
2Horse(Equine)
2Wildboar(Susscrofa)
1Cat(Feline)
1Macacamulatta
1Monkey
1Pig(Porcine)
1RhesusMonkey
Source
Escherichiacoli(E.coli)
88Escherichiacoli(E.coli)
9Yeast
1HEK-293Cells
1HEK293
1Human
1HumanCells
1InsectCells
1MammalianCells
1Wheatgerm
ProteinType
Recombinant
Purificationtag/Conjugate
ThisCCL5proteinislabelledwithHistag.
Application
ELISA
Options
Bulkdiscount
Supplier
SupplierProductNo.
SequenceSPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS
CharacteristicsPleaseinquireifyouareinterestedinthisrecombinantproteinexpressedinE.coli,mammaliencellsorbybaculovirusinfection.Beawareaboutdifferencesinpriceandleadtime.
Purity90%
BackgroundChemoattractantforbloodmonocytes,memoryT-helpercellsandeosinophils.Causesthereleaseofhistaminefrombasophilsandactivateseosinophils.BindstoCCR1,CCR3,CCR4andCCR5.OneofthemajorHIV-suppressivefactorsproducedbyCD8+T-cells.RecombinantRANTESproteininducesadose-dependentinhibitionofdifferentstrainsofHIV-1,HIV-2,andsimianimmunodeficiencyvirus(SIV).TheprocessedformRANTES(3-68)actsasanaturalchemotaxisinhibitorandisamorepotentinhibitorofHIV-1-infection.ThesecondprocessedformRANTES(4-68)exhibitsreducedchemotacticandHIV-suppressiveactivitycomparedwithRANTES(1-68)andRANTES(3-68)andisgeneratedbyanunidentifiedenzymeassociatedwithmonocytesandneutrophils.Ref.3Ref.8Ref.10Ref.11Ref.12
MolecularWeight11.9kD
UniProtP13501
PathwaysCellularResponsetoMoleculeofBacterialOrigin,RegulationofG-ProteinCoupledReceptorProteinSignaling,SmoothMuscleCellMigration
Comment

Theyeastproteinexpressionsystemisthemosteconomicalandefficienteukaryoticsystemforsecretionandintracellularexpression.Aproteinexpressedbythemammaliancellsystemisofveryhigh-qualityandclosetothenaturalprotein.Butthelowexpressionlevel,thehighcostofmediumandthecultureconditionsrestrictthepromotionofmammaliancellexpressionsystems.Theyeastproteinexpressionsystemserveasaeukaryoticsystemintegratetheadvantagesofthemammaliancellexpressionsystem.Aproteinexpressedbyyeastsystemcouldbemodificatedsuchasglycosylation,acylation,phosphorylationandsoontoensurethenativeproteinconformation.Itcanbeusedtoproduceproteinmaterialwithhighaddedvaluethatisveryclosetothenaturalprotein.Ourproteinsproducedbyyeastexpressionsystemhasbeenusedasrawmaterialsfordownstreampreparationofmonoclonalantibodies.

RestrictionsForResearchUseonly
FormatLyophilized
Concentration0.2-2mg/mL
BufferTris-basedbuffer,50%glycerol
HandlingAdviceRepeatedfreezingandthawingisnotrecommended.Storeworkingaliquotsat4°Cforuptooneweek
Storage-20°C
StorageCommentStoreat-20°Cforextendedstorage,conserveat-20°Cor-80°C
SupplierImages
SDS-PAGE (SDS) image for Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91), (full length) protein (His tag) (ABIN1046691)Chemokine(C-CMotif)Ligand5(CCL5)(AA24-91),(fulllength)protein(Histag)
BackgroundpublicationsCapoulade-Métay,Ayouba,Kfutwah,Lole,Pêtres,Dudoit,Deterre,Menu,Barré-Sinoussi,Debré,Theodorou:"AnaturalCCL5/RANTESvariantantagonistforCCR1andCCR3."in:Immunogenetics,Vol.58,Issue7,pp.533-41,2006(PubMed).

Schall,Jongstra,Dyer,Jorgensen,Clayberger,Davis,Krensky:"AhumanTcell-specificmoleculeisamemberofanewgenefamily."in:Journalofimmunology(Baltimore,Md.:1950),Vol.141,Issue3,pp.1018-25,1988(PubMed).


新闻动态
行业前沿
技术文章
最新产品

188进口试剂采购网 www.188bio.cn -中国试剂网,试剂网,化学试剂网,国药试剂,抗体公司,试剂公司,试剂盒公司,苏州试剂公司,北京化学试剂公司,天津化学试剂,试剂商城,试剂代理,流式抗体 细胞库查询 sitemap