DESCRIPTION:Human recombinant PB1-2 (second bromodomain of polybromo-1). PB1, a chromatin targeting component of the PBAF (SWI/SNF-B) chromatin-remodeling complex, comprises six tandem bromodomains. Mutations in PB1, including PB1-2, occur frequently in renal cancers. Among the acetylated lysines of histone N-terminal tails, PB1-2 binds preferentially to H3K14Ac.
ACCESSION #: NM_018313
Uniprot Link
INCLUDES AMINO ACIDS: 178-291
TAG(S): N-terminal His-tag
MW: 15.7 kDa
EXPRESSION SYSTEM: E. coli
SUPPLIED AS: Solution of purified recombinant protein in 50 mM Tris/HCl, pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v)
STORAGE: -70°C. Thaw quickly and store on ice before use. The remaining, unused, undiluted protein should be snap frozen, for example in a dry/ice ethanol bath or liquid nitrogen. Minimize freeze/thaws if possible, but very low volume aliquots (<5 µl) or storage of diluted protein is not recommended.
View Product Data Sheet
Substantial Discounts Available on Bulk Quantities
SouthernBiotech/Goat Anti-Human Lambda-Alexa Fluor® 555/2070-32/1.0 mg
vectorlabs/Biotinylated Aleuria Aurantia Lectin (AAL)/B-1395/1 mg
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Mouse IgG)/PK-6102/1 kit
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Universal)/PK-6200/1 kit
vectorlabs/Unconjugated Musa Paradisiaca (Banana) Lectin (BanLec)/L-1410/5 mg
GiottoBiotech/Calmodulin N60D/5 mg/G02CLM60cn