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NSJ Bio/ABCC11 Antibody (F48871)/0.4 ml/F48871-0.4ML188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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NSJ Bio/ABCC11 Antibody (F48871)/0.4 ml/F48871-0.4ML

Description

ATP-binding cassette sub-family C member 11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.

Application Notes

Titration of the ABCC11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 343-372 from the human protein was used as the immunogen for this ABCC11 antibody.

Storage

Aliquot the ABCC11 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.

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