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NSJ Bio/ABCC9 Antibody (F46433)/0.08 ml/F46433-0.08ML188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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NSJ Bio/ABCC9 Antibody (F46433)/0.08 ml/F46433-0.08ML

Description

ATP-binding cassette sub-family C member 9 is a member of thesuperfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- andintra-cellular membranes. ABC genes are divided into seven distinctsubfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Thisprotein is a member of the MRP subfamily which is involved inmulti-drug resistance. This protein is thought to formATP-sensitive potassium channels in cardiac, skeletal, and vascularand non-vascular smooth muscle. Protein structure suggests a roleas the drug-binding channel-modulating subunit of theextrapancreatic ATP-sensitive potassium channels. No disease hasbeen associated with this gene thus far. Alternative splicing ofthis gene results in several products, two of which result fromdifferential usage of two terminal exons and one of which resultsfrom exon deletion.

Application Notes

Titration of the ABCC9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 640-669 from the human protein was used as the immunogen for this ABCC9 antibody.

Storage

Aliquot the ABCC9 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.

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