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LKT/17U03B1ETHYNYLESTRADIOL/E7731/1 g
ProductIDE7731
CasNo.77538-56-8
Purity≥98%
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

17-α-ethynylestradiolisasyntheticestrogenreceptor(ER)agonistclinicallyusedincontraceptivemedications.Inpregnantrats,17-α-ethynylestradioldecreasesplateletactivatingfactoracetylhydrolaseactivity,inducingprematurebirth.17-α-ethynylestradiolalsodisplaysweakantioxidativeactivityinlipidperoxidationassaysinlivermicrosomes.Bothacuteandchronicexposureofwildlife(particularlyfish)to17-α-ethynylestradiolleadstofeminizationofmales(throughtheinductionofvitellogeninproduction),inhibitingfertility.

ProductInfo

CasNo.

77538-56-8

Purity

≥98%

Formula

C20H24O2

FormulaWt.

296.40

IUPACName

(8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

Synonym

Ethinylestradiol

MeltingPoint

182-183°C

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

E7731MSDSPDF

InfoSheet

E7731InfoSheetPDF

References

KiddKA,BlanchfieldPJ,MillsKH,etal.Collapseofafishpopulationafterexposuretoasyntheticestrogen.ProcNatlAcadSciUSA.2007May22;104(21):8897-901.PMID:17517636.

SchultzIR,SkillmanA,NicolasJM,etal.Short-termexposureto17alpha-ethynylestradioldecreasesthefertilityofsexuallymaturingmalerainbowtrout(Oncorhynchusmykiss).EnvironToxicolChem.2003Jun;22(6):1272-80.PMID:12785584.

YasudaK,FurukawaM,JohnstonJM.Effectofestrogensonplasmaplatelet-activatingfactoracetylhydrolaseandthetimingofparturitionintherat.BiolReprod.1996Jan;54(1):224-9.PMID:8838020.

LacortM,LealAM,LizaM,etal.Protectiveeffectofestrogensandcatecholestrogensagainstperoxidativemembranedamageinvitro.Lipids.1995Feb;30(2):141-6.PMID:7769970.


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