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Adipogen/XL019/SYN1191M050/50 mg
MoreInformation
ProductDetails
SynonymsXL-019
ProductTypeChemical
Properties
FormulaC25H28N6O2
MW444.5
CAS945750-13-0
PurityChemicals≥95%
AppearanceSolid.
SolubilitySolubleinDMSO.
DeclarationManufacturedbySynKinase.
OtherProductDataTarget:PI3K-mTOR|KinaseGroup:LipidKinase|Substrate:Lipid

ClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
InChiKeyISOCDPQFIXDIMS-HSZRJFAPSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage+4°C
Use/StabilityStableforatleast1yearafterreceiptwhenstoredat+4°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
XL019isapotentJAK2inhibitor(IC(50)of2nM)withexcellentselectivityversustheothermembersoftheJAKkinasefamily(JAK1,IC(50)of130nM;JAK3,IC(50)of250nM;TYK2,IC(50)of340nM).
ProductReferences
  1. SARandinvivoevaluationof4-aryl-2-aminoalkylpyrimidinesaspotentandselectiveJanuskinase2(JAK2)inhibitors:T.Forsyth,etal.;Bioorg.Med.Chem.Lett.22,7653(2012)

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