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Adipogen/Takeda6d/SYN1168M050/50 mg
MoreInformation
ProductDetails
SynonymsTakeda6d
ProductTypeChemical
Properties
FormulaC27H19ClFN5O3S
MW548.0
CAS1125632-93-0
PurityChemicals≥95%
AppearanceSolid.
SolubilitySolubleinDMSO.
DeclarationManufacturedbySynKinase.
OtherProductDataTarget:B-RAF-VEGFR2|KinaseGroup:TKL|Substrate:Serine-Threonine

ClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
InChiKeyMDPMAXSABUPRJI-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StabilityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
Takeda-6dhaspotentinhibitoryactivityinbothB-RAFwithanIC(50)of7.0nMandVEGFR2withanIC(50)of2.2nM.
ProductReferences
  1. DesignandsynthesisofnovelDFG-outRAF/vascularendothelialgrowthfactorreceptor2(VEGFR2)inhibitors.1.Explorationof[5,6]-fusedbicyclicscaffolds:M.Okaniwa,etal.;J.Med.Chem.55,3452(2012)

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