Deprecated: Creation of dynamic property cls_session::$session_data_table is deprecated in /www/sites/www.188bio.com/index/systems/cls_session.php on line 49
FabGennix/Atypical Chemokine Receptor D6 Antibody/ACRD6-612AP188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
您好,欢迎您进入188进口试剂采购网网站! 服务热线:4000-520-616
蚂蚁淘商城 | 现货促销 | 科研狗 | 生物在线
产品资料

FabGennix/Atypical Chemokine Receptor D6 Antibody/ACRD6-612AP

  • Description

General Information

Product

D6 Antibody

Description

Affinity Purified Atypical chemokine receptor 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-378 mouse Atypical chemokine receptor 2protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage

Application Protocol

Dot Blot

1:10,000

ELISA

1:10,000

Immunohistochemistry1:50-1:150
Immunoprecipitation1:200

Western Blot

1:500

Protein

Uniprot #

O08707

Overview

Controls chemokine levels and localization via high-affinity chemoking binding that is uncoupled from classic liand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Acts as a regulator of inflammatory leukocyte interactions with lymphatic endothelial cells and is required for immature/mature dendritic cells discrimination.

Molecular Function

Chemokine Receptor activity; Scavenger receptor activity

Subcellular Location

Early endosome; Recycling endosome; Cell membrane; Multi-pass membrane protein

Expression

Endothelial cells lining afferent lympatics in dermis and lymph nodes. Also found n subcapsular and medullary sinuses, tonsillar lympatic sinuses and lymphatics in mucosa and submucosa of appendix, small intestine, and large intestine.

Structure

C-terminal cytoplasmic tail controls phosphorylation, stability, intracellular trafficking and chemokine scavenging properties.

Alternative Nomenclature

ACKR2 antibody

Atypical chemokine receptor 2 antibody

Chemokine binding protein 2 antibody

Chemokine receptor CCR 10 antibody

Chemokine receptor CCR 9 antibody

CMKBR9 antibody

Protein information supplied by UniProt

新闻动态
行业前沿
技术文章
最新产品