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FabGennix/TOMM7 Antibody/TOM7-701AP

  • Description
  • Specification Sheet

General Information

Product

TOMM7 Antibody

Description

Affinity Purified Mitochondrial import receptor subunit TOM7 homolog Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Pig, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human Mitochondrial import receptor subunit TOM7 homolog protein.

Accession #

NCBI: NP_061932.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q9P0U1

Overview

Required for assembly and stability of the TOM complex. Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria.

Molecular Function

Cellular protein metabolic process; Protein targeting to mitochondrion

Subcellular Location

Membrane, Mitochondrion, Mitochondrion outer membrane

Structure

Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70).

Alternative Nomenclature

Mitochondrial import receptor subunit TOM7 homolog antibody TOM7 antibody

Protein information supplied by UniProt

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