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Sciencell/Recombinant Human DES (1-3) IGF-1/105-01B/1 Ea

Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
HumanDes(1-3)Insulin-likeGrowthFactor-I(IGF-I)isa67aminoacidanalogofhumanIGF-IlackingtheN-terminaltripeptideGly-Pro-Glu.HumanDes(1-3)IGF-IismorepotentthanIGF-Iinvitroandinvivo.ThisincreasedpotencyisduetoreducedbindingofhumanDes(1-3)IGF-ItomostoftheIGFbindingproteinswhichnormallyinhibittheBIOLOGicalactionsofIGF-I.HumanDes(1-3)IGF-IbindstotheType1IGFreceptorwithsimilaraffinitytofulllengthIGF-I.

Specifications:

CatalogNo.105-01B
CountryofManufactureUnitedStates
ProductCoderhDES1-3/IGF1
Size/Quantity20μg
ProductUseThisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
StorageThislyophilizedpreparationisstableat2-8°C,butshouldbekeptat-20°Cforlongtermstorage,preferablydesiccated.Uponreconstitution,thepreparationisstableforuptooneweekat
ShippingInfoDryice
AASequenceTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
SourceEscherichiacoli.
MolecularWeight7.4kDa,asinglenon-glycosylatedpolypeptidechaincontaining67aminoacidresidues.
Purity>97%bySDS-PAGEandHPLCanalyses.
BiologicalActivityTheED50wasdeterminedbyacellproliferationassayusingserumfreehumanMCF-7cellsislessthan2ng/ml,correspondingtoaspecificactivityof>5�10^5IU/mg.
PhysicalAppearanceSterileFilteredWhitelyophilized(freeze-dried)powder.
FormulationLyophilizedfroma0.2μmfilteredconcentratedsolutioninPBS,pH7.4.
EndotoxinLessthan1EU/μgofrHuDES1-3/IGF1asdeterminedbyLALmethod.
ReconstitutionWerecommendthatthisvialbebrieflycentrifugedpriortoopeningtobringthecontentstothebottom.Reconstituteinsteriledistilledwateroraqueousbuffercontaining0.1%BSAtoaconcentratio
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