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Sciencell/Recombinant Human VEGF165/105-05/1 Ea

Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
VEGFisapotentgrowthandangiogeniccytokine.Itstimulatesproliferationandsurvivalofendothelialcells,andpromotesangiogenesisandvascularpermeABIlity.Expressedinvascularizedtissues,VEGFplaysaprominentroleinnormalandpathologicalangiogenesis.SubstantialevidenceimplicatesVEGFintheinductionoftumormetastasisandintra-ocularneovascularsyndromes.VEGFsignalsthroughthethreereceptors;fms-liketyrosinekinase(flt-1),KDRgeneproduct(themurinehomologofKDRistheflk-1geneproduct)andtheflt4geneproduct.

Specifications:

CatalogNo.105-05
CountryofManufactureUnitedStates
ProductCoderhVEGF165
Size/Quantity2μg
ProductUseThisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
StorageStoreat-20°Cafterreceiving.UponReconstitution,storeat2-8°Cforuptooneweek.Formaximalstability,aliquotandstoreat-20°C.Avoidrepeatedfreeze/thawcycles.
ShippingInfoDryice
AASequenceAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQENPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
SourceEscherichiacoli
MolecularWeightApproximately38.2kDadisulfide-linkedhomodimericproteinconsistingoftwo165aminoacidpolypeptidechains.
Purity>95%bySDS-PAGEandHPLCanalyses.
BIOLOGicalActivityFullybiologicallyactive.TheED50is1-8ng/ml,asdeterminedbyHUVECcellproliferation.
PhysicalAppearanceWhitelyophilizedpowder.
FormulationLyophilizedfroma0.2μmfilteredsolutioninPBS,pH7.4.
Endotoxin
ReconstitutionReconstituteinsteriledistilledwatercontaining0.1%BSAtoaconcentrationof0.1-1.0mg/mL.
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