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Sciencell/Recombinant Murine EGF/125-04/1 Ea

Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
EGFwasoriginallydiscoveredincrudepreparationsofnervegrowthfactorpreparedfrommousesuBMAxillaryglandsasanactivitythatinducedearlyeyelidopening,incisoreruption,hairgrowthinhibition,andstuntingofgrowthwheninjectedintonewbornmice.EGFisapotentgrowthfactorthatstimulatestheproliferationofvariousepidermalandepithelialcells.Additionally,EGFhasbeenshowntoinhibitgastricsecretion,andtobeinvolvedinwoundhealing.EGFsignalsthroughareceptorknownasc-erbB,whichisaclassItyrosinekinasereceptor.ThisreceptoralsobindswithTGF-alphaandVGF(vacciniavirusgrowthfactor).

Specifications:

CatalogNo.125-04
CountryofManufactureUnitedStates
ProductCodermEGF
Size/Quantity100μg
ProductUseThisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
StorageStoreat-20°Cafterreceiving.UponReconstitution,storeat2-8°Cforuptooneweek.FormaximalstABIlity,aliquotandstoreat-20°C.Avoidrepeatedfreeze/thawcycles.
ShippingInfoDryice
SynonymsUrogastrone,URG
AASequenceNSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQTRDLRWWELR
SourceEscherichiacoli
MolecularWeight6.0kDa,asinglenon-glycosylatedpolypeptidechaincontaining53aminoacids,including3intramoleculardisulfide-bonds.
Purity>96%bySDS-PAGEandHPLCanalyses.
BIOLOGicalActivityFullybiologicallyactive.TheED50is1x10^7units/mg.
PhysicalAppearanceWhitelyophilizedpowder.
FormulationLyophilizedfroma0.2μmfilteredsolutioninPBS,pH7.4.
Endotoxin
ReconstitutionReconstituteinsteriledistilledwatercontaining0.1%BSAtoaconcentrationof0.1-1.0mg/mL.
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