TheproteinencodedbythisgeneisachemokinereceptorbelongingtotheGprotein-coupledreceptorsuperfamily.Thefamilymembersarecharacterizedbythepresenceof7transmembranedomainsandnumerousconservedaminoacids.ThisreceptorismostcloselyrelatedtoRBS11andtheMIP1-alpha/RANTESreceptor.Ittransducesasignalbyincreasingtheintracellularcalciumionslevel.Theviralmacrophageinflammatoryprotein-IIisanantagonistofthisreceptorandblockssignaling.Twoalternativelysplicedtranscriptvariantsencodingthesameproteinhavebeenfoundforthisgene.
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