Human, Recombinant, 0.1 mg CDH13, Human, Recombinant,  0.1 mg 货号：BM51250.1MG 品牌：Advanced Biomatrix Equl意果_易扩_AdvancedBioMatrix_DivBio_Drummond_Geni

Human,Recombinant,0.1mgCDH13,Human,Recombinant, 0.1mg货号：BM-5125-0.1MG品牌：AdvancedBiomatrix-Equl意果_易扩_AdvancedBioMatrix_DivBio_Drummond_Genie_Glascol_Megazyme_Phadebas_Worthington

英文名：CDH13,Human,Recombinant, 0.1mg

货号：BM-5125-0.1MG

规格：0.1mg

品牌：AdvancedBiomatrix

CDH13geneencodesamemberofthecadherinsuperfamily.TheencodedproteinislocalizedtothesurfaceofthecellmembraneandisanchoredbyaGPImoiety,ratherthanbyatransmembranedomain.Theproteinlacksthecytoplasmicdomaincharacteristicofothercadherins,andsoisnotthoughttobeacell-celladhesionglycoprotein.Thisproteinactsasanegativeregulatorofaxongrowthduringneuraldifferentiation.Italsoprotectsvascularendothelialcellsfromapoptosisduetooxidativestress,andisassociatedwithresistancetoatherosclerosis.Thegeneishypermethylatedinmanytypesofcancer.

Full-lengthextracellulardomainofhumanCDH13gene(139-693aa)wasconstructedwith31N-terminalT7/HistagandexpressedinE.coliasinclusionbodies.Thefinalproductwasrefoldedusingouruniquetemperatureshiftinclusionbodyrefoldingtechnologyandchromatographicallypurified.

Formulatedin20mMpH8.0Tris-HClBuffer,withproprietaryformulationofNaCl,KCl,EDTA,L-arginine,DTTandGlycerol.

Keepat-20Cforlongtermstorage.Productisstableat4Cforatleast30days

MASMTGGQQMGRGHHHHHHGNLYFQGGEFELSIVVSPILIPENQ
RQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTG
SVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQN
DNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLR
YNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKY
ELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQAT
VEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHT
NPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPS
STATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATD
PDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVD
NSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAE
VCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKIS
KINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQV
CSCRNSKVDCNAAG