Product Name | Alpha-1-Antitrypsin |
Source | Human Plasma |
Catalogue Number | 106-11 |
Purity | > 95% (SDS-PAGE) |
Form | Lyophilized |
Protein | Reported in mg/vial (A280, E0.1%=0.433) |
Formulation | Lyophilized from sodium phosphate buffer |
Reconstitution | De-ionized H2O |
Storage | -20°C |
Recertification | 3 years |
Molecular Weight | ~54,000 |
UNSPSC code | 51131904 |
Synonyms | A1AT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase |
Lee Biosolutions is the leading supplier of human plasma Alpha-1-Antitrypsin (A1AT) for medical research and diagnostic manufacturing.
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Human alpha 1 Antitrypsin or Human A1-antitrypsin (A1AT), also known as serum trypsin inhibitor, protects tissue from enzymes from inflammatory cells, especially elastase and is present in human blood. Disorders of the enzyme include human alpha-1 antitrypsin deficiency, a hereditary disorder in which lack of Human alpha-1 Antitrypsin AAT (A1AT) leads to uninhibited tissue breakdown during inflammation.
Studies indicate that this causes pulmonary emphysema and leads to liver cirrhosis in severe cases. Human alpha-1 antitrypsin protects the lungs from the harmful effects of human neutrophil elastase.
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