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LKT/ISOPROTERENOL HYDROCHLORIDE/I7259/100 g

ProductIDI7259
CasNo.51-30-9
Purity≥98%
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Isoproterenolisanon-selectiveβ-adrenergicreceptoragoNISTthatisclinicallyusedtotreatbradycardia,heartblock,andasthma;itexhibitsantihypertensive,bronchodilatory,andanti-asthmaactivities.Isoproterenolincreasessystolicbloodpressureanddecreasesdiastolicbloodpressure,producinganoveralldecreaseinmeanarterialpressure.Thepositiveinotropicactionofisoproterenolisoftenusedtoinducecardiacdysfunctionormyocardialinfarctioninresearchmodels.Isoproterenolalsoinducesrelaxationofairwaysmoothmuscle.

ProductInfo

CasNo.

51-30-9

Purity

≥98%

Formula

C11H17NO3•HCl

FormulaWt.

247.72

IUPACName

hydron;4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;chloride

Synonym

(+/-)-Isoprenalinehydrochloride;1-(3",4"-Dihydro-xyphenyl)-2-isopropylaminoethanolHydrochloride;N-Isopropyl-DL-noradrenalineHydrochloride

MeltingPoint

165.5-170°C

Solubility

Solubleinwater(>300mg/L),ethanol(20mg/mL),andmethanol.

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

I7259MSDSPDF

InfoSheet

I7259InfoSheetPDF

References

GongLL,FangLH,WangSB,etal.Coptisineexertcardioprotectiveeffectthroughanti-oxidativeandinhibitionofRhoA/Rhokinasepathwayonisoproterenol-inducedmyocardialinfarctioninrats.Atherosclerosis.2012May;222(1):50-8.PMID:22387061.

GumpA,HaughneyL,FredbergJ.Relaxationofactivatedairwaysmoothmuscle:relativepotencyofisoproterenolvs.tidalstretch.JApplPhysiol(1985).2001Jun;90(6):2306-10.PMID:11356796.

GreenJF.Mechanismofactionofisoproterenolonvenousreturn.AmJPhysiol.1977Feb;232(2):H152-6.PMID:842647.

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