MedKooCat#:314234
Name:Ospemifene
CAS#:128607-22-7
ChemicalFormula:C24H23ClO2
ExactMass:378.13866
MolecularWeight:378.89
ElementalAnalysis:C,76.08;H,6.12;Cl,9.36;O,8.45
Synonym:Osphena
IUPAC/ChemicalName:2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol
InChiKey:LUMKNAVTFCDUIE-VHXPQNKSSA-N
InChiCode:InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-
SMILESCode:ClCC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCO)C=C2)C3=CC=CC=C3
1:SoeLH,WurzGT,KaoCJ,DegregorioMW.Ospemifeneforthetreatmentofdyspareuniaassociatedwithvulvarandvaginalatrophy:potentialbenefitsinboneandbreast.IntJWomensHealth.2013Sep25;5:605-11.doi:10.2147/IJWH.S39146.Review.PubMedPMID:24109197;PubMedCentralPMCID:PMC3792833.
2:ElkinsonS,YangLP.Ospemifene:firstglobalapproval.Drugs.2013May;73(6):605-12.doi:10.1007/s40265-013-0046-y.Review.PubMedPMID:23605694.
3:McCallJL,DeGregorioMW.Pharmacologicevaluationofospemifene.ExpertOpinDrugMetabToxicol.2010Jun;6(6):773-9.doi:10.1517/17425255.2010.487483.Review.PubMedPMID:20429673.
4:GennariL,MerlottiD,ValleggiF,NutiR.Ospemifeneuseinpostmenopausalwomen.ExpertOpinInvestigDrugs.2009Jun;18(6):839-49.doi:10.1517/13543780902953715.Review.PubMedPMID:19466874.
5:GennariL.OspemifeneHormos.CurrOpinInvestigDrugs.2004Apr;5(4):448-55.Review.PubMedPMID:15134288.
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