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Innovative Research/Mouse WISP1/CCN4 ELISA Kit/IRKTAH5480/1 Ea

ProductDescription

MouseWISP1/CCN4ELISAKit-1Kit(96Wells)
OurMouseWISP1/CCN4ELISAKitisasandwichELISAintendedforthequantitativedeterminationofmouseWISP1incellculturesupernates,serumandplasma(heparin,EDTA).

WISP1(WNT1-InducIBLeSignalingPathwayProtein1),alsoknownasCCN4,isamatricellularproteinthatinhumansisencodedbytheWISP1gene.WISP1isinducedbyWNT1andbelongstotheCCNfamily,whichincludesconnectivetissuegrowthfactor,cysteine-rich-61,andnephroblastomaoverexpressed.ByuseofrADIationhybridmappingpanels,theWISP1wasmappedtochromosome8q24.1-q24.3,roughly4MbdistaltoMYC.Itfoundthat2distinctsystemsdemonstratedthatWISPinductionwasassociatedwithexpressionofWNT1.WISP1genomicDNAwasamplifiedincoloncancercelllinesandinhumancolontumors,anditsRNAwasoverexpressedin84%oftumorsexaminedcomparedwithpatient-matchednormalmucosa.

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