Sedanolide is an inducer of glutathione S-transferases (GSTs) and inhibitor of chemically induced carcinogenesis. It was shown to inhibit cyclooxygenase-1 and -2 (Cox-1 and -2) as well as topoisomerase I and topoisomerase II (Topo I and Topo II). Sedanolide is mosquitocidal, nematicidal and antifungal.
1. Zheng, G.Q., et al. 1993. Nutr. Cancer. 19: 77-86. PMID: 8446516 2. Momin, R.A., et al. 2001. J. Agric. Food Chem. 49: 142-145. PMID: 11305251 3. Woods, J.A., et al. 2001. In. Vitr. Mol. Toxicol. 14: 233-240. PMID: 11846995 4. Momin, R.A. and Nair, M.G. 2002. Phytomedicine. 9: 312-318. PMID: 12120812
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