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Santa Cruz/A 987306 (CAS 1082954-71-9)/sc-291776

A 987306(CAS1082954-71-9)

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应用;A 987306 is a potent and selective histamine H4 receptor antagonist
CAS号码:1082954-71-9
分子量:327.42
分子式:C18H25N5O
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

A 987306 is a potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). This compound displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors.

参考文献

Liu et al (2008) cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. J.Med.Chem. 51 7094. Leurs et al (2009

物理状态:
Solid
溶解度:
DMSO (100 mM) and ethanol (100mM)
保存:
Store at -20° C
仅供科研使用。不可用于诊断或治疗。
运输:
Not available for sale outside of the United States.
PubChem CID:
25109291
SMILES:
C1CC[[email protected]]2[[email protected]@H](C1)C3=C(O2)CCC4=C3N=C(N=C4N5CCNCC5)N

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