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Santa Cruz/AC 45594 (CAS 13037-86-0)/sc-203798

AC 45594(CAS13037-86-0)

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应用;AC 45594 is an agonist at the orphan nuclear receptor steroidogenic factor-1
CAS号码:13037-86-0
纯度:97%
分子量:208.3
分子式:C13H20O2
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

AC 45594 is a selective inverse agonist at the orphan nuclear receptor SF-1 (steroidogenic factor-1) (IC50= 50-100 nM). Displays no activity at estrogen, LRH-1, ROR, ERR or Nurr receptors. Inhibits SFRE-mediated transcription.

参考文献

Del Tredici et al (2008) Identification of the first synthetic steroidogenic factor 1 inverse agonist.: pharmacological modulation of steroidogenic enymes. Mol.Pharmacol. 73 900.

物理状态:
Solid
溶解度:
Soluble in water (partly), DMSO (100 mM), and ethanol (100 mM).
保存:
Store at 4° C
熔点:
60-63° C (lit.)
沸点:
~325.3° C at 760 mmHg (Predicted)
密度:
~1.0 g/cm3 (Predicted)
折射率:
n20D 1.51 (Predicted)
IC50:
Steroidogenic factor-1: IC50 = 50 - 100 nM; Androgen Receptor: IC50 = 14.79 µM (rat)
pK值:
pKa: 10.35 (Predicted)
仅供科研使用。不可用于诊断或治疗。
德国水公害等级:
3
RTECS:
SL4860000
PubChem CID:
25641
MDL 号码:
MFCD00002338
Beilstein 注册:
1871129
SMILES:
CCCCCCCOC1=CC=C(C=C1)O

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