Trevigen/Anti-PARP Monoclonal Antibody (clone C2-10)/4338-MC-50/50 μg

Description

ANTIBODYCONCENTRATION
Providedin1XPBScontaining0.1mg/mlBSAand0.01%sodiumazide.
ThismousemonoclonalantibodyisanIgG1.
CONTROL
PARPHSAEnzymeavailableseparately.
IMMUNOGEN
CalfThymusPARP-1
SPECIFICITY
Detectsthe114kDaPARP-1holoenzyme,85kDaapoptosis-related,andnecrosis-related50/62/74kDacleavagefragmentsfromhuman,monkey,hamster,ratandmousebutnotchicken.
STORAGE
Storeat4°Cforatleast1month,orstorealiquotsat-20°C.
APPLICATIONS
WesternBlotAnalysisandImmunocytochemistry

Bookmarkingpromotersinmitoticchromatin:poly(ADP-ribose)polymerase-1asanepigeneticmark
Lodhi,N.,Kossenkov,A.V.andTulin,AlexeiV.
NucleicAcidsRes.,May2014;10.1093/nar/gku415.
http://nar.oxfordjournals.org/cgi/content/abstract/gku415v1

TNF-α-mediatedcaspase-8activationinducesROSproductionandTRPM2activationinadultventricularmyocytes
“StéphanieRoberge,JulienRoussel,DanielC.Andersson,AlbanoC.Meli,BastienVidal,FlorenceBlandel,JohannaT.Lanner,Jean-YvesLeGuennec,AbramKatz,HåkanWesterblad,AlainLacampagne,andJérémyFauconnier”
CardiovascRes,Jul2014;103:90–99.
http://cardiovascres.oxfordjournals.org/cgi/content/abstract/103/1/90

RoleofActivatingTranscriptionFactor3(ATF3)inEndoplasmicReticulum(ER)Stress-inducedSensitizationofp53-deficientHumanColonCancerCellstoTumorNecrosisFactor(TNF)-relatedApoptosis-inducingLigand(TRAIL)-mediatedApoptosisthroughUp-regulationofDeathReceptor5(DR5)byZerumboneandCelecoxib
MakotoEdagawa,JunyaKawauchi,ManabuHirata,HirotoGoshima,MakotoInoue,TatsuroOkamoto,AkiraMurakami,YoshihikoMaehara,andShigetakaKitajima
J.Biol.Chem.,Aug2014;289:21544–21561.

TheobromineincreasesNAD+/Sirt-1activityandprotectsthekidneyunderdiabeticconditions
AlexandrosPapADImitriou,KamilaC.Silva,ELISAB.M.I.Peixoto,CynthiaM.Borges,JacquelineM.LopesdeFaria,JoséB.LopesdeFaria
mJPhysiolRenalPhysiol,Feb2015;308:F209–F225
http://ajprenal.physiology.org/cgi/content/abstract/308/3/F209

“Poly(ADP-ribose)Polymerase1ModulatesInteractionofthe
NucleotideExcisionRepairFactorXPC-RAD23BwithDNAvia
Poly(ADP-ribosyl)ation”
EkaterinaA.Maltseva,NadejdaI.Rechkunova,MariaV.Sukhanova,andOlgaI.Lavrik
J.Biol.Chem.,Sep2015;290:21811–21820.
http://www.jbc.org/cgi/content/abstract/290/36/21811

“CoordinatedRegulationofTIP60andPoly(ADP-Ribose)Polymerase1inDamaged-ChromatinDynamics”
“MasaeIkura,KanjiFuruya,AtsuhikoFukuto,RyoMatsuda,JunAdachi,TomonariMatsuda,AkiraKakizuka,andTsuyoshiIkura”
Mol.Cell.Biol.,May2016;36:1595–1607.
http://mcb.asm.org/cgi/content/abstract/36/10/1595