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TulipBiolabs/Anti-pADPR, clone 10H/50 µg/1020

Poly(ADP-ribose)ImmunohistochemicalStaining
ofRatLiver

<clickimagetoenlarge>

●Anti-pADPr,clone10H,mousemonoclonalantibodyThismousemonoclonalantibody,clone10H,recognizespoly(ADP-ribose).ItwasdevelopedandoriginallydescribedbyH.Kawamitsu etal. (1984) Biochemistry23,3771.Poly(ADP-ribose)isapolymersynthesizedbyaclassofenzymesnamedpoly(ADP-ribose)polymerase(PARP).UsingNAD+assubstrate,PARPcatalyzestheformationofthepolymerpADPr,withchainlengthsrangingfrom2to300residues,containingapproximately2%branchinginthechain.pADPrbecomesattachedtonuclearproteins,andtoPARPitself(automodification).Usesfortheclone10Hmonoclonalantibodyhasbeendescribedextensivelyintheliterature,andincludeWesternblotting,immunostaining(seebelow),ELISA-basedPARPactivityscreen,andimmunodotblot. 

Pleaseseethe Cat.#1020Datasheet(pdf) foracompletedescriptionincludingpublications.

Alsoavailablecarrier-proteinfree(neat). PleaseseetheCat.#1020/NDatasheet(pdf) foracompletedescription.

Contactusforspecialordersorlargerquantities.

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