ABL2isaproto-oncogene,locatedonchromosome1q25.2,thatisexpressedinbothnormalandtumorcellsandfunctionsincytoskeletalrearrangements.ItisinvolvedintranslocationwiththeETSVariant6geneinleukemia.Frequenttranslocation,t(1;12)(q25;p13),isassociatedwithacutenon-lymphoblasticleukemia.OtherdiseasesassociatedwiththeABL2geneareacutemyeloidleukemiawitheosinophilia.
OurABL2BreakApartFISHProbecanbeusedtodetectarearrangementoftheABL2gene.Theprobecomeslabeledinorangeandgreen,andyoumayalsochoosetocustomizetheprobetomeetyourneeds.
*USA–ASR,EU–CEMarked(Orange-Greencoloroptiononly)
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